重组人NF-kB抑制物alpha (IkappaBalpha),Recombinant Human NF-kappaB inhibitor alpha (IkappaBalpha) Certificate of Analysis and Data Sheet Source: E.Coli Catalog No. PKA-313 Background :The NF-kappaB inhibitor, IkappaB, has classically bee
2. NFKBIA:编码IκBα(inhibitor of NF-kB alpha),是NF-kB活性的主要负调节器。它通过绑定NF-kB亚基,防止其进入细胞核并结合到DNA上。 3. RELA:也称为p65,是一种在NF-kB复合物中高度表达的核因子。p65是NF-kB如此活跃和多样性的关键成员之一,能够与其他成员形成多种不同的复合物。 4. NFKB2:编码p100...
大多数NF-KB蛋白N末端都有一个高度保守、由300个氨基酸组成的Rel同源性结构域(Relhomology domain,RHD),负责与DNA结合、二聚体化及与NF-KB抑制性蛋白(inhibitor κB,IKB-)家族成员相互作用。 IKB-是一类基因家族,包括IκBα、IκBβ、IκB、IκBγ、Bcl-3以及NF-κB1、NF-κB2的前体P105、P100,其功能主要...
klB902Mu 小鼠心肌钙黏蛋白(CDHH)ELISA试剂盒现货供应 ELISA Kit for Cadherin, Heart (CDHH) klH776Mu 小鼠中间α-球蛋白抑制因子H4(ITIH4)ELISA试剂盒现货供应 ELISA Kit for Inter Alpha-Globulin Inhibitor H4 (ITIH4)大鼠NFKB激活蛋白(NKAP)检测试剂盒...
0 评论次数: 0 文档热度: 文档分类: 待分类 文档标签: kB作用损伤急性肺损伤和NFNFKBkB在急性肺损伤中的作用中作用 系统标签: 损伤急性粒细胞机制tnf作用 α和NF-KB在急性肺损伤中的作用机制120包头医学院JOURNALOFBAOTOUMEDICALCOLLEGE2011年第27卷第2期VoL27No.22011TNF一和NF—KB在急性肺损伤中的作用机制李彬...
In subject area: Biochemistry, Genetics and Molecular Biology Featured on this page Chapters and Articles You might find these chapters and articles relevant to this topic. miRNA-223 at the crossroads of inflammation and cancer Jacob Jeffries, ... Qing Deng, in ...
Tak PP,Gerlag DM,Aupperle KR,et a1.Inhibitor of nuclear factor kappaB kinase beta is a key regulator of synovial inflammation.Arthritis Rheum,2001,44(8):1897—1907. [21] Pulai JI,Chen H,Im HJ,et a1.NF—kappa B mediates the stimulation of cytokine and chemokine expression by human ...
NFkB inhibitor alpha downregulates the activity of NFkB. In previous studies the NFKBIA 3'UTR AA genotype was associated with CD, while the NFKB1–94ins/delATTG mutation increased the risk for UC. Our aim was to study the above polymorphisms and patients' response to medical therapy and/or...
blocked by an NFkB peptide inhibitor and expression of a dominant negative mutant IkB伪, but not by inhibitors of the MAPK/ERK1/2 or PI3K pathways. ... Anna,Leychenko,Eugene,... - 《Plos One》 被引量: 86发表: 2011年 Activation of nuclear factor-kB in the spinal cord of experimental...
Nucleus. Cytoplasm. Note=Colocalized with DDX1 in the nucleus upon TNF-alpha induction. Nuclear, but also found in the cytoplasm in an inactive form complexed to an inhibitor (I-kappa-B). Colocalizes with GFI1 in the nucleus after LPS stimulation. ...