Definition, Biology, and History of Oligometastatic and Oligoprogressive DiseaseKeywords Molecular biologyneoplasm stagingoligometastasistumor biomarkersHistorical theories of metastasis have been informed by the seed and soil hypothesis, the Halsteadian paradigm proposing an orderly spread from local to distant...
Definition noun A disease due to the presence of an infective particle, especially a microbial pathogenic agent that is capable of being transmitted to another host. Supplement Different microbial agents can bring disease to their host. They include the pathogenic viruses, bacteria, fungi, protozoa,...
Even though the primary defect in CF is monogenic by definition, the manifestation of endophenotypes such as diabetes or liver disease as well as disease severity are rather polygenic by nature, meaning that searching for modifiers in CF or any other monogenic disorder raises the same hurdles as ...
Irrespective of the human perspective on the definition of an insect pest, they exist in our agroecosystems. Phytophagous and hematophagous insects sustain their life through vegetation or animal blood. From time to time we need to reduce pest population size or control of their spread, in ...
The general inability of the milky disease bacteria to grow and sporulate on standard media has challenged taxonomic definition, and initial classification based on morphotype has been overtaken by molecular genetics methods. In the earliest studies, Rippere et al. (1998) examined a bank of 34 st...
The UK cohort representing rheumatoid arthritis (RA) was defined based on electronic health records of the ICD10 codes M069, M059, and M060, and the definition of the cohort representing ankylosing spondylitis (AS) was based on the ICD10 code M45. This matched the definition of the respectiv...
the definition of phenotypes of interest in specific cell types in order to functionally characterize a gene of interest is a prerequisite that can lead to the development of hypothesis-driven approaches. Thus, the vast majority of post-GWAS functional studies have been based on aspects of the am...
4. Investigating SSBs using molecular and cell biology tools 5. Investigating SSBs using next-generation sequencing tools 6. Single-cell DNA Sequencing 7. Concluding remarks CRediT authorship contribution statement Declaration of Competing Interest Acknowledgements Data availability ReferencesShow full outline ...
Definition Chapters and Articles Related Terms Recommended Publications Featured Authors Chapters and Articles You might find these chapters and articles relevant to this topic. Bacterial Diseases Lakshmi P. Kotra, in xPharm: The Comprehensive Pharmacology Reference, 2007 Introduction Bacterial diseases are ...
The definition of the “prodromal behavioral repertoire” based on fine-grained behavioral cues detected in-the-wild and associated with the brain-, body-, and social-level neurodegenerative manifestations. (2) The analysis and validation of computational models in AI that facilitated deciphering the ...