Diabetes is a chronic disease that occurseitherwhen the pancreas does not produce enough insulinorwhen the body cannot effectively use the insulin it produces. Insulin is a hormone that regulates blood sugar. Hyperglycaemia, or raised blood sugar, is a common effect...
Type 1 diabetes, diabetic kidney disease, diabetic neuropathy, diabetic retinopathyObjectives: Diabetic kidney disease (DKD) is an independent predictor of cardiovascular morbidity and mortality in type 1 diabetes (T1D). We aimed to explore clinical and biochemical factors, including the achievement of...
Ndufs4, a subunit of complex I, is a regulator of the electron transport chain. Here, the authors show that forced expression of Ndufs4 in podocytes improves the assembly of respiratory supercomplexes, maintains cristae integrity, and mitigates the progression of diabetic kidney disease ...
V. Risk factors and urinary biomarkers of non-albuminuric and albuminuric chronic kidney disease in patients with type 2 diabetes. World J. Diabetes 10, 517–533 (2019). Article PubMed PubMed Central Google Scholar Nowak, N. et al. Markers of early progressive renal decline in type 2 ...
Considerations for individualization of BP targets include both anticipated benefits (e.g., higher absolute benefit for patients with higher underlying cardiovascular or kidney disease risk) and potential risks (e.g., ability to tolerate pharmacotherapy without experiencing adverse effects). For patients ...
Over time, high blood glucose damages nerves and blood vessels, leading to complications such as heart disease, stroke, kidney disease, blindness, dental disease, and amputations. Other complications of diabetes may include increased susceptibility to other diseases, loss of mobility with aging, depres...
(i.e., atherosclerotic cardiovascular disease, heart failure and chronic kidney disease [CKD]), suggesting that these additional benefits (i.e., cardio/reno-protective and mortality-reducing effects) are worth considering in m...
Risk factors of chronic kidney diseases in Chinese adults with type 2 diabetes. who were enrolled in the Risk Factor Assessment and Management Programme for Patients with Diabetes Mellitus (RAMP-DM) of Hong Kong from July 2014 to Jun... Lin,Yang,T Kit,... - 《Scientific Reports》 被引量...
Kidney dysfunction is a strong predictor of end-stage renal disease and cardiovascular (CV) events. The main goal was to study the clinical correlates of diabetic kidney disease in a large cohort of patients with type 2 diabetes mellitus (T2DM) attending 236 Diabetes Clinics in Italy. Methods ...
Methodology Retrospective cohort study of non-diabetic pediatric patients, aged 6 months to 19 years, who underwent a first kidney transplant during 1995-2016. We estimated the cumulative incidence rate and used multivariable logistic regression to identify the diabetogenic risk factors for PTDM. ...