Antiganglioside antibodies are implicated in many neurological disorders such as acute and chronic polyradiculoneuropathies which includes different variants of Guillain-Barré syndrome, chronic inflammatory demyelinating polyradiculoneuropathy and multifocal motor neuropathy. Presence of such antibodies in ...
We have studied the presence of IgG and IgM anti-gangliosides antibodies by enzyme-linked immunosorbent assay (ELISA) and dot blot immune stain in 34 patients with positive serology for Chagas' disease, divided into three groups (G); GI: no cardiac symptoms, normal ECG, and chest X-ray; ...
Antiganglioside antibodies in acute self-limiting ataxic neuropathy: incidence and significance. J Neuroimmunol. 2001;120:78–83.Serrano-Munuera C, Gallardo E, Rojas R, et al. Antiganglioside antibodies in acute self-limiting ataxic neuropathy: incidence and significance. J Neuroimmunol 2001;120:...
Anti-ganglioside GM1 is very useful in the identification of ganglioside GM1 and in immunotargeting cells expressing GM1. Several gangliosides have been found to have an elevated expression in tumor cells. Many therapeutic treatments of tumor cells are being investigated using antibodies to target cel...
4. F. Notturno MD, C. Caporale MD, A. Uncini MD “Acute sensory ataxic neuropathy with antibodies to GD1b and GQ1b gangliosides and prompt recovery” Muscle & Nerve, Vol. 37(2) pg. 265–268, 2008 产品名称 Anti-ganglioside GD2 (polyclonal antibody to GD2, isotype IgG, IgM) ...
et al. Auto-antibodies to contactin-associated protein 1 (Caspr) in two patients with painful inflammatory neuropathy. Brain 139, 2617–2630 (2016). Article PubMed Google Scholar Naik, Gs et al. Anti-ganglioside antibodies profile in guillain-barré syndrome: correlation with clinical features, ...
IgM paraproteins associated with autoimmune peripheral neuropathy and anti-Pr cold agglutinins react with sialic acid epitopes present on disialylated gangliosides including GD1b, GT1b, GQ1b, and GD3. A causal relationship between the paraprotein and the neuropathy has never been proven experimentally...
(absorbancyofseraaddedtowellswithoutganglioside),whichinterferewiththeaccurateassessmentofthefinespecificityandsensitivityoftheseantibodies.Thisinvestigationidentifiesfactorselevatingthebackgroundvaluesand/ordecreasingthefinespecificity,anddescribesstrategiestominimizetheirinfluence.Usingseraofneuropathyandmelanomapatients,wefound...
In contrast, our patient was clinically stable and did not have antiganglioside antibodies. Nerve conduction studies showed pseudo-CBs rather than true CBs. We suggest that pseudo-CBs with ITD can reveal heterogeneous axonal regeneration as a sequel of a severe multifocal vasculitic neuropathy. This...
Both IgM antigangliosides and antigalactocerebrosides antibodies disappeared in seven patients with definite but clinically inactive NPM. The analysis of these autoantibodies showed an important role predictive for NPM in SLE; the negative test decreases the chance of the NPM. This is a preview of ...